Characteristics of Studies Investigating CVM Related to ADT.
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Abbreviations: LOE = level of evidence; CVM = cardiovascular mortality; ADT = androgen deprivation therapy; CAB = combined androgen blockade; GnRH = gonadotropin-releasing hormone (leuteinizing hormone releasing hormone, LHRH); AA = oral antiandrogens; RP = Radical prostatectomy/Curative Treatment; RT = radiation therapy; WW/AS = watchful waiting(WW)/active surveillance (AS); HRs = Hazard Ratios; RRs = Risk Ratios; AMI = Acute Myocardial Infarction; SD = standard deviation; NA = not applicable; CaPSURE = Cancer of the Prostate Strategic Urologic Research Endeavor; ICES = Institute for Clinical Evaluative Sciences; NPCR = National Prostate Cancer Register; SEER = Surveillance, Epidemiology and End Results Medicare data; GPRD = UK General Practice Research Database.amean or median.bcompared with WW/AS.cThe HR/RR was directly given in the publication.dCombined estimates from all types of ADT with random effects meta-analysis.Characteristics of Studies Investigating CVM Related to ADT.



