Short-term maternal and neonatal outcomes in preterm (< 33 weeks gestation) Cesarean deliveries under general anesthesia with deferred cord clamping

Deferred cord clamping (DCC) is beneficial for preterm infants, but there are concerns about the safety of DCC during Cesarean deliveries (CD) under general anesthesia (GA). We evaluated maternal and neonatal outcomes in preterm CD under GA vs. regional anesthesia (RA) after implementing 180 s of DCC. This retrospective single-center observational study included CD at < 33 weeks of gestation, delivered between January 2018 and December 2023. The cord was clamped before 180 s for concerns of maternal bleeding or infant apnea after 30-45 s stimulation. Multivariable regression analysis was used to assess the effect of anesthesia type and DCC on outcomes, adjusting for confounders. This study included 170 mothers and 194 infants, 84.9 % of the infants received DCC ≥ 60 s. The GA group had higher emergency CD and lower median duration of DCC (105 s vs 180 s, p = <0.001) compared to RA. GA was associated with lower odds (95 % CI) of UA pH < 7 [0.1, (0.0, 0.6)], base deficit ≥ 1..., Materials and Methods
We conducted a single-center, retrospective study of all CD < 33 weeks gestation performed between January 2018 and December 2023. Institutional Review Board (IRB) approval was obtained (#24-007). Cases of lethal fetal anomalies were excluded.
Data on maternal demographics, pregnancy characteristics, delivery data, and maternal and infant outcomes were obtained from standardized reports in the electronic health record. Details on anesthesia timing, indication for CD, and indication for GA were confirmed with manual chart review. Anesthesia type was categorized as GA (if GA administration occurred before delivery of the infant) or RA, including spinal, epidural, or combined spinal epidural anesthesia. CD urgency was recorded by the delivering obstetrician at the time of surgery; “Emergency/STAT” was defined as need for immediate delivery due to impending fetal or maternal death or injury (e.g. fetal bradycardia.). Maternal blood loss was determined quantitatively..., # Data from: Short-term Maternal and neonatal outcomes in preterm (< 33 weeks gestation) Cesarean deliveries under general anesthesia with deferred cord clamping

Dataset DOI: [10.5061/dryad.ffbg79d78](10.5061/dryad.ffbg79d78)

## Description of the data and file structure

Data on maternal demographics, pregnancy characteristics, delivery data, and maternal and infant outcomes were obtained from standardized reports in the electronic health record. Details on anesthesia timing, indication for CD, and indication for GA were confirmed with manual chart review.

### Files and variables

#### Data is available as a single csv file: “datadryad_de-identified_data.csv”

Missing values are indicated by blank cells

Variables, definitions, units, and legends are provided in the table belolw:

 

| Variable | variable label | vallab | legend |
| :----------------- | :---------------------..., This was a retrospective study that was approved by the institutional review board with waiver of consent. The data does not contain any direct identifiers. The two indirect identifiers were birth weight and gestational age. The birth weight was converted to weight categories in 100 g intervals, and gestational age was converted to categories in completed weeks of gestation., Direct primary identifiers were removed from the dataset and the indirect identifiers of birth weight was categorized in 100g increments and gestational age were categorized in weeks.
Written consent was not obtained for this study. This is a retrospective observational study that was approved by the institutional review board with waiver of consent.