Crystal structure of human DNA cross-link repair 1A in complex with hydroxamic acid inhibitor (compound 48).
收藏Protein Data Bank Japan2024-09-11 更新2026-04-19 收录
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Crystal structure of human DNA cross-link repair 1A in complex with hydroxamic acid inhibitor (compound 48). Descriptor: 4-[[(2~{S})-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]amino]-~{N}-prop-2-enyl-quinazoline-2-carboxamide, DNA cross-link repair 1A protein, ZINC ION Authors: Yosaatmadja, Y, Newman, J.A, Baddock, H.T, Bielinski, M, von Delft, F, Bountra, C, McHugh, P.J, Schofield, C.J, Gileadi, O. Deposit date: 2023-01-19 Release date: 2024-01-31 Last modified: 2024-09-11 Method: X-RAY DIFFRACTION (1.46 Å) Cite: Cell-active small molecule inhibitors validate the SNM1A DNA repair nuclease as a cancer target. Chem Sci, 15, 2024
创建时间：
2023-01-19
