miRNA expression profiling of locally advancer cervical cancer

MiRNA expression in totally 200 locally advanced cervical tumor biopsies were analysed by sequencing of small RNAs with Illumina HiSeq 2500. Based on the RNA isolation protocols, 90 samples were assigned to an experimental cohort, and 110 samples were assigned to a validation cohort (validation cohort1). The miRNA expression data was used to investigate miRNAs associated with prognosis and clinocopathological features in cervical cancer patients. Further we used the miRNA expression data to discover target genes by mathed sample miRNA-mRNA expression analysis with mRNA expression data. miRNA expression profiling by small RNA sequencing of totally 200 tumor biopsies of locally advanced cervical cancer. ***Raw data are not publicly available due to patient privacy concerns. ---------------------------------------------- Authors state the following: Does not contains raw data files due to patient privacy concerns (seq. data). Raw data files will be submitted to the EGA-database for controlled access.