Cd59b

ENCODES a protein that exhibits complement binding; INVOLVED IN negative regulation of activation of membrane attack complex; negative regulation of apoptotic process; negative regulation of complement-dependent cytotoxicity; PARTICIPATES IN coagulation cascade pathway; complement system pathway; ASSOCIATED WITH decreased erythrocyte cell number; increased red blood cell distribution width; increased susceptibility to type III hypersensitivity reaction; ASSOCIATED WITH acute necrotizing pancreatitis; Alcoholic Liver Diseases; anterior uveitis; FOUND IN compact myelin; extracellular space; sarcolemma; INTERACTS WITH (+)-schisandrin B; 1,3-Propane sultone; 17alpha-ethynylestradiol

编码一种表现出补体结合特性的蛋白质；参与膜攻击复合物的负调节激活；细胞凋亡过程的负调节；补体依赖性细胞毒性的负调节；参与凝血级联途径；补体系统途径；与红细胞数量减少、红细胞分布宽度增加以及对III型超敏反应易感性增加相关；与急性坏死性胰腺炎、酒精性肝病、前葡萄膜炎相关；存在于紧密髓鞘、细胞外空间、肌细胞膜；与（+）五味子素B、1,3-丙烷磺酮、17α-乙炔雌二醇相互作用。