RNA-seq sequencing data from individual (S)-AAC-resistant HAP-1 clones
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP286867
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In order to identify the secondary mechanism responsible for (S)-AAC cytotoxic effects on human cells, (S)-DAC resistant clone DACR#A4 was mutagenized with EMS and the mutagenized population was selected with a 10 uM lethal concentration of a (S)-AAC. Individual clones were isolated (AACR clones). Seven of them, plus the DACR#A4 clone, were submitted to RNA-seq to identify mutations conferring resistance to (S)-AAC.
创建时间：
2021-12-31
