Intrachain dynamics at pH 7.4 and pH 3.5, reported as observed relaxation time, τR (µs).

Observed intrachain diffusion time obtained from FCS measurements as described in the Materials and Methods (4≤n≤12 for all constructs; error is standard deviation of the mean). Significance level in the difference in dynamics of βS or γS relative to αS (*); significance level in the difference in dynamics for each protein at pH 3.5 relative to pH 7.4 (+). */+ indicates results that are significant at the 5% level using a two-tailed Mann-Whitney U-test. AH–amphipathic helix motif-containing construct; LF–flexible loop forming construct; NAC–non-amyloid beta component or hydrophobic core construct; CT–C-terminal construct.