In our study, PRDM14 and NFRkB were found to enhance the reprogramming of human fibroblasts to hiPSCs in the presence of OCT4, SOX2, KLF4, with/without c-MYC (OSK/OSKC). To examnie if the obtained hiP

NIAID Data Ecosystem50

Misdirection of axonal outgrowth of nerve fibers after nerve injury and repai...

神经再生

轴突导向机制

Peripheral nerve injuries are common and lead to life-long disability for affected individuals in spite of surgical treatments. Yet an unsolved clinical problem is misdirected...

B2FIND20

C2C12 murine myoblast cell line and 48 h 10 uM BIO treated C2C12 cellulate. Mus musculus

细胞重编程

心肌细胞去分化机制

In urodele amphibians, limb regeneration involves the dedifferentiation of muscle myotubes into single cells that may acquire pluripotent potential. We have employed small molecules (myoseverin and BI

NIAID Data Ecosystem50

Additional file 5 of Unraveling the 2,3-diketo-l-gulonic acid-dependent and -independent impacts of l-ascorbic acid on somatic cell reprogramming

细胞重编程

维生素C生化作用

Additional file 5: Table S4. Reagents and resources used in the current studies.

NIAID Data Ecosystem40