Transcriptional profile analysis of Caco-2 cell line upon inflammatory signals and ER stress induction

We stimulated Caco-2 cells, with the TLR5 agonist flagellin (Fl), with the chemical ER stress inducer thapsigargin (TG), or a combination of both (TGFl). This strategy mimics a pro-inflammatory response in the presence of ER stress. Different treatments are represented as C (non-treated cells), Fl (treated with flagellin 1 μg / mL for 2 hours), TG (treated with TG at 1 μM for 5 hours), or X (treated with 1 μM TG for 5 hours, and with 1 μg / mL Fl for additional 2 hours).