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Transcriptome study of the deletion of vacuolar protein sorting related vps13 and vps21 in Trichoderma reesei

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https://www.ncbi.nlm.nih.gov/sra/SRP344433
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The disruption of vacuolar protein sorting related genes vps13 and vps21 in filamentou fungi Trichoderma reesei resulted in a dramtic increase in cellulase transcription especially in the late Avicel induction phase, relieving the RESS (REpression under Secretion Stress) effect. Great interest arisen concered about the reason and underlying mechanism of vps13 and vps21 disruption for increased cellulase transcription. Thus, transcriptome analysis through RNA-Seq could give a deep insight of the potential pathways involved in enhanced cellulase transcription in late Avicel induction. Overall design: Mycelia sampled of wild type, and its vps mutant ?vps13 and ?vps21, from Avicel induction medium at day 4 were conducted for RNA-Seq
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2021-11-11
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