mousepost V2.0

mousepost V2.0 aims to provide an overview of the non-synonymous mutations, both SNP and small insertions/deletions, that affect the protein coding transcripts of 52 (from 36) often used laboratory strains of mice. We identified mutations on a per codon basis and classified them in 4 main groups.

MousePost V2.0 旨在全面呈现可影响52种（源自36种）常用实验小鼠品系蛋白质编码转录本的非同义突变，涵盖单核苷酸多态性（Single Nucleotide Polymorphism, SNP）与小型插入/缺失突变两类变异。本数据集以密码子为单位完成突变鉴定，并将其划分为四大主要类别。

搜集汇总

背景与挑战

背景概述

mousepost V2.0是一个数据集，旨在概述52种常用实验室小鼠品系中影响蛋白质编码转录本的非同义突变（SNP和小插入/缺失）。它按密码子识别突变，并将其分为Stop Gained、Stop Loss、Start Codon和Mutated四个主要类别，以预测对蛋白质功能的影响。