Transcriptomic profiling of MLL-ENL and delta YEATS mutant. Transcriptomic profiling of MLL-ENL and delta YEATS mutant
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA870725
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资源简介:
To investigate the contribution of ENL YEATS domain and downstream sequences in MLL-ENL leukemogenesis program, we generated MLL-ENL and MLL-ENL ∆YEATS (ENL aa372-559) cell lines by retrovirally introducing these constructs into lineage negative hematopoietic stem and progenitor cells (HSPCs). Overall design: We then perform gene expression profiling using dataset obtained from RNA-seq experiment of MLL-ENL and MLL-ENL ∆YEATS, with 2 technical replicates each.
创建时间:
2022-08-18



