Total expected mean cost per patient, weighted by care seeking and utilisation patterns (US$, 2004).

aAll these estimations were obtained from the consensuses of the expert panel (refers to figure 1).bLifetime costs were calculated as the present value of annual costs accounting for the disease duration (minus ten-year delay for seeking care) and 3% discount rate.cPatients who do not seek treatment care, apart from palliative care near death, were assumed to spend an equivalent cost to two years in intermediate level of care (value also annualised).