Cryo-EM structure of the unliganded human melanocortin receptor 5 (MC5R)-Gs complex

Cryo-EM structure of the unliganded human melanocortin receptor 5 (MC5R)-Gs complex Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,HiBiT, Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... Authors: Feng, W.B, Zhou, Q.T, Zheng, C, Yang, D.H, Wang, M.W. Deposit date: 2024-10-18 Release date: 2025-08-06 Last modified: 2025-08-13 Method: ELECTRON MICROSCOPY (2.86 Å) Cite: Structural basis for the constitutive activity of the melanocortin receptor family. Structure, 33, 2025