TO ANTIBIOTICS RESISTANCE: CONSEQUENCES OF MISUSE AMONG THE POPULATION OF UZBEKISTAN AND PREVENTIVE MEASURES

It is observed that approximately 70-80% of the population of Uzbekistan misuses antibiotics. This situation to antibiotics resistant bacteria strains appearance to be and clinical in practice serious to problems take is coming. This in the article The mechanisms of antibiotic resistance, in particular the processes of genetic information exchange between bacteria: conjugation, transformation and transduction, are examined in detail. Beta-lactamases, aminoglycoside-modifying enzymes and other inactivation mechanisms are also analyzed. The article covers the routes of infection transmission, the consequences of not completing the full course of treatment, and the scientific rationale for the use of high-dose antibiotics in children.