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Transcriptomic study of NR8383 rat macrophages cells following exposure to multi-walled carbon nanotubes (NRCWE006)

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To identify differentially expressed genes and key biological pathways that define toxicity following nanomaterial exposure, we performed microarray analyses on NR8383 macrophages exposed for 4 h to 1 cm²/cm² of multi-walled carbon nanotubes (NRCWE006 - Mitsui-7). This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement N°. 686098

为鉴定纳米材料暴露后毒性相关的差异表达基因(differentially expressed genes)与关键生物通路,我们对暴露于1 cm²/cm²剂量的多壁碳纳米管(multi-walled carbon nanotubes,NRCWE006 - Mitsui-7)的NR8383巨噬细胞开展了4小时的微阵列分析(microarray analyses)。本项目获欧盟“地平线2020”研究与创新计划资助,资助协议编号为686098。

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