Data for "Anti-Breast Cancer Stem Cell Activity of Titanocene Complexes of Non-Steroidal Anti-Inflammatory Drugs"
收藏DataCite Commons2025-10-15 更新2026-05-07 收录
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https://figshare.le.ac.uk/articles/dataset/Data_for_Anti-Breast_Cancer_Stem_Cell_Activity_of_Titanocene_Complexes_of_Non-Steroidal_Anti-Inflammatory_Drugs_/29665502/1
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资源简介：
Titanocene(IV)-NSAID complexes Cp<sub>2</sub>Ti(mefenamate)<sub>2</sub> (<b>4</b>) and Cp<sub>2</sub>Ti(flufenamate)<sub>2</sub> (<b>5</b>) show enhanced redox stability and potent cytotoxicity against breast cancer stem cells (CSCs), with <b>5</b> rivaling salinomycin and cisplatin. Complex <b>5</b> induces DNA damage and apoptosis, and its nanoparticle encapsulation improves biocompatibility. This is the first report targeting breast CSCs with titanocene-based metallodrugs.
提供机构：
University of Leicester
创建时间：
2025-09-16
