Characteristics of differentially methylated regions with at least 50% difference in methylation percentage, the same directional change and shared between and specific to the affected twin sisters.

Boxes 1 and 2: Methylation percentages of CpG islands as analyzed in replicates in 2 discordant monozygotic twins sisters. Box 3: Localization and associated genes (if known) of the 12 regions potentially associated with cardiovascular risk in adult women following pregnancies complicated by pre-eclampsia and/or HELLP.