KRAS and MEK activation promote antisense oligonucleotide uptake and activity by limiting collagen production
收藏NIAID Data Ecosystem2026-03-12 收录
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Using RNAseq we describe transcriptional changes downstream of MEK1 affecting RNA kncokdown following free uptake RNaseH1 gapmer antisense oligonucleotides We perform RNAseq on cell lines with a stimulated MAPK pathway via inducible expression of KRAS(G12D), inducible expression of MEK1(S218/S222DD) and by stimulation with the PKC activator, PMA
创建时间：
2021-04-24
