Breadth of CMI response among HCV-responders to peptides derived from GT-1b and GT-4a.

PBMC were stimulated in triplicates with two sets of seven pooled overlapping 15-mer HCV genotype GT-1b, and 4a peptide antigens (E2 through M) for 16h as described in the Subjects and Methods section. The average number of HCV-specific SFC for the individual peptide pools (E2 through M±SEM) in the responding subjects is recorded for each pool and is shown for both genotypes. The responses shown are after subtraction of the DMSO control. The correlation of the CMI response to both HCV antigen sets in the different HCV proteins is also shown.
**High correlation.