The recent development of high throughput DNA provides an alternative new method for describing and quantifying transcriptome. During the analysis process, the user is nevertheless always confronted t
Background Chromosomal aberrations, such as translocations or chromosomal inversions, are a major cause of acquired or inherited genetic disease in humans. Next-generation, ultra high-throughput sequ
Rationale:Cultured human bronchial epithelia (HBE) are the gold standard model for assessing the efficacy of small molecule therapies in cystic fibrosis (CF). However, these cells are difficult to acc
