A class of hydrazones are active against non-replicating Mycobacterium tuberculosis
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https://figshare.com/articles/dataset/A_class_of_hydrazones_are_active_against_non-replicating_i_Mycobacterium_tuberculosis_i_/7219043
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There is an urgent need for the development of shorter, simpler and more tolerable drugs to treat antibiotic tolerant populations of Mycobacterium tuberculosis. We previously identified a series of hydrazones active against M. tuberculosis. We selected five representative compounds for further analysis. All compounds were active against non-replicating M. tuberculosis, with two compounds demonstrating greater activity under hypoxic conditions than aerobic culture. Compounds had bactericidal activity with MBC/MIC of
创建时间：
2018-10-17
