Interactions of SDS with A8-35 monitored by isothermal titration calorimetry.

Demicellization of SDS in the presence of various A8-35 concentrations: (A) Differential heating power, Δp, versus time, monitored during the titration of 10 mM SDS and 20 µM A8-35 into 20 µM A8-35. (B) Normalized heats of reaction, QS, versus SDS concentration in the cell, [SDS], resulting from the dilution of micellar SDS solutions (10-13 mM) in the presence of A8-35 at A8-35 concentrations of 5 µM (△), 10 µM (O), 20 µM (◊), 40 µM (◃), 60 µM (▹), 80 µM (), 100 µM (☆), 120 µM (□), and 140 µM (+).