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Exome sequencing of thymus transplantation based spontaneous murine T cell acute lymphoblastic leukemia (T-ALL) model

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NIAID Data Ecosystem2026-04-25 收录
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We adapted a spontaneously-arising, genetically-heterogeneous, thymic transplantation-based murine model of T-ALL, recapitulating key histopathological and genetic features of the human disease, to the preclinical testing of targeted and immune-directed therapies. Overall design: Wild-type thymus-derived T-ALL samples were subjected to exome sequencing

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2019-10-09
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