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Allelic specificity of IGH-DUX4 translocation in acute lymphoblastic leukemia (ALL) [Hi-C]

NIAID Data Ecosystem2026-03-11 收录

白血病遗传学

染色体易位

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE115491 数据链接链接失效反馈

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In Nalm6, mono-allelic interaction between IGH enhancer and IGH promoter was found from Hi-C data. Hi-C

应用场景：

创建时间：

2019-08-10

白血病遗传学

靶向治疗耐药性

Objective: The development of tyrosine kinase inhibitors (TKIs) has significantly improved the treatment of chronic myeloid leukemia (CML). However, approximately one third of patients are resistant t

NIAID Data Ecosystem60

Supplementary Material for: B-Cell Acute Lymphoblastic Leukemia with iAMP21 in a Patient with Constitutional Ring Chromosome 21

白血病遗传学

染色体21

Pediatric B-cell acute lymphoblastic leukemia (B-ALL) is associated with various specific cytogenetic and molecular markers that significantly influence treatment and prognosis. Intrachromosomal ampli

NIAID Data Ecosystem40

Percent of translocation junctions without microhomology and with insertions.

基因组结构变异

染色体易位

Percent of translocation junctions without microhomology and with insertions.

NIAID Data Ecosystem30

The RS4;11 cell line as a model for leukaemia with t(4;11)(q21;q23): revised characterisation of cytogenetics features

白血病遗传学

融合基因验证

Figure 1. Representative karyotype of RS4;11 obtained by M-FISH. In this metaphase the karyotype was determined to be 46,XX,t(4;11)(q21;q23),i(7)(q10),i(8)(q10). Arrows indicate the deri

DataCite Commons2020-08-27 更新50

Additional file 2 of A genome-wide survey of mutations in the Jurkat cell line

基因组结构

白血病遗传学

Supplementary Table S1. Long deletions found in Jurkat with matches to pathogenic variants in dbVar. Matches were determined by 90% reciprocal overlap. All database matches are included with one dbVar

Figshare2018-05-09 更新30

Allelic specificity of IGH-DUX4 translocation in acute lymphoblastic leukemia (ALL) [Hi-C]

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