Impact of cognitive performance and normal aging on transcriptomic changes in the prefrontal cortex of rats

We investigated how cognitive stimulation impacts gene expression in the prefrontal cortex (PFC), a brain region known to regulate higher cognitive functions including the control of attention, in young and aged rats. 2x2 design: 2 (cognitive performance [2 levels: performing, non performing) x 2 (age [2 levels: young, old])