Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-700

Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-700 Descriptor: (1R)-4-([1,1'-biphenyl]-4-yl)-1-phosphonobutane-1-sulfonic acid, Dehydrosqualene synthase Authors: Liu, C.I, Jeng, W.Y, Wang, A.H, Oldfield, E. Deposit date: 2007-11-11 Release date: 2008-03-11 Last modified: 2026-05-27 Method: X-RAY DIFFRACTION (2.03 Å) Cite: A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science, 319, 2008