Pharmacokinetics of DB829 in vervet monkeys with second stage HAT after the 5th intramuscular dose.
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Group 1 = 5 mg/kg × 5 consecutive days; Group 2 = 5 mg/kg × 5 alternating days; Group 3 = 2.5 mg/kg × 5 consecutive days; F, female; M, male; Tmax, time to reach Cmax; Cmax, maximum concentration; AUClast, AUC from time 0 to the last measurable concentration; AUC(0-∞), AUC from 0 to infinite time; Cl/F, apparent clearance; t½, terminal half-life;† = last measurable concentration varied between monkeys (112–490 days).Pharmacokinetics of DB829 in vervet monkeys with second stage HAT after the 5th intramuscular dose.
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2015-12-02
