Transcription profiling of mouse liver with CEBPa wild type and knockout animals

Expression analysis of CEBPa knockout effects on gene expression in adult mouse liver. We used a conditional knock out strategy to delete CEBPa specifically in adult mouse hepatocytes and analysed the resulting changes in gene expression by means of microarrays.CCAAT增强子结合蛋白α（CEBPa）敲除对成年小鼠肝脏基因表达影响的表达分析。本研究采用条件性基因敲除策略，特异性敲除成年小鼠肝细胞中的CEBPa，并通过微阵列技术分析由此产生的基因表达变化。