Single-unit auditory nerve fibre responses of young-adult and aging gerbils

This dataset was collected to study the functional consequences of age-related hearing loss for the auditory nerve, which carries acoustic information from the periphery to the central auditory system. Using high-impedance glass electrodes, raw voltage traces and spike times were recorded from more than one thousand single fibres of the auditory nerve of young-adult, middle-aged, and old Mongolian gerbils raised in a quiet environment. The dataset contains not only responses to simple acoustic stimuli to characterize the fibres, but also to more complex stimuli, such as speech logatomes in background noise and Schroeder-phase stimuli. A software toolbox is provided to search through the dataset, to plot various analysed outcomes, and to give insight into the analyses. This dataset may serve as a valuable resource to test further hypotheses about age-related hearing loss. Additionally, it can aid in optimizing available computational models of the auditory system, which can contribute to..., The dataset presented here contains the raw waveforms and spike times from single auditory nerve fibres of young-adult, middle-aged, and old gerbils, while presenting a variety of acoustic stimuli to assess the functioning of the single fibres. Gerbils were anesthetized with ketamine/xylazine injections and auditory brainstem responses (a type of compound response) were recorded to derive a measure of their general hearing sensitivity. The auditory nerve was approached dorsally through the cerebellum and a sharp, high-impedance glass electrode was slowly moved through the nerve. Single-unit recordings were made for as long as the surgical preparation was stable. Afterwards, spikes in the data were identified, data files were organized into folders of one single unit, data were analysed to characterize the fibre, and a set of criteria was used to ensure the single unit derived from the auditory nerve bundle. Methods are described in detail in the accompanying manuscript. , , # Single-unit auditory nerve fibre responses of young-adult and aging gerbils

[https://doi.org/10.5061/dryad.qv9s4mwn4](https://doi.org/10.5061/dryad.qv9s4mwn4)

This dataset contains the raw and processed data derived from single-unit auditory nerve fibre recordings in young-adult and aging gerbils. Using high-impedance, glass electrodes, raw voltage traces and spike times were recorded from over one-thousand single fibres of the auditory nerve of Mongolian gerbils raised in a quiet environment. Software was written and tested in MATLAB version R2023b.

## Description of the data and file structure

All raw, processed, and metadata of one animal is saved in one datafile ('G#.mat'). Such a .mat file contains one variable, 'exp', which is structured equally between all experiments. The content of each field in this struct is described in the document 'Data_Structure.pdf'. An overview of the metadata of each animal, e.g. age, hearing sensitivity, presented complex acoustic stimuli, numbe...