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MINDY1 drives metabolic-immune crosstalk through an OGT–UGP2–UDPG axis to promote immunosuppressive macrophage reprogramming in hepatocellular carcinoma

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To explore the proteins that are potentially regulated by MINDY1, we performed immunoprecipitation-based mass spectrometry (IP-MS) following ectopic expression of Flag-MINDY1 and immunoprecipitation. We noticed that the O-Linked N-Acetylglucosamine (GlcNAc) Transferase (OGT) was immunoprecipitated by MINDY1

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2026-02-28
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