The first genome assembly of the amphibian nematode parasite (Aplectana chamaeleonis). Aplectana chamaeleonis

Cosmocercoid nematodes are common parasites in the digestive tract of amphibians. Genomic resources are important for understanding the evolution of a species and the molecular mechanisms of parasite adaptation. So far, no genome resource of Cosmocercoid has been reported. In 2020, a massive infection of the parasite was found in the small intestine of an amphibian toad, causing a severe intestinal blockage. We identified this parasite as A. chamaeleonis morphologically. Here, we report for the first time a highly contiguous A. chamaeleonis genome with a genome size of 1.1Gb. The repeat content in the Ascaris genome is 72.45%, and the total length is more than 742Mb. This study is of great significance for understanding the evolution of Cosmocercoid, and also provides a molecular basis for Cosmocercoid infection and control.