Specific oncogenic drivers differently shaped the composition and functional diversity of immune cells in the microenvironment of experimental gliomas

We performed spatial transcriptomics to profile spatial localization and intercations of cell populations within GL261 glioma mouse model. Overall design: Two healthy (sham operated) and two GL261 bearing hemispheres from C57BL/6 male mice were used for the analysis using 10X Visium Spatial Transcriptionics kit.