Abnormal findings in cytogenetic and FISH analysis performed on twenty-one independently derived hNPC lines.

*- Cytogenetic G-band karyotyping results with the percent abnormal based on analysis of 20 metaphase cells, † - FISH analysis results showing the percent of cells displaying either trisomy 7 (+7) or trisomy 19 (+19) based on counting signals in at least 200 nuclei. Normal results from a cytogenetic or FISH study are stated. Tests that were not performed are represented by “NP” in the relevant column. Whenever an aberration was detected, the absolute number or the range of per cent abnormal cells from passage to passage is indicated.
Δ - The results for multiple passages from one line or its derivatives tested are listed in different rows.
# - The passage range in a row indicates testing of the line or its derivative at different passages.
¶ - Five out of 21 lines were identified as susceptible to +7 and only M031 CTX was identified with +19.
∧- B001 and B003 CTX lines were obtained from Down's syndrome patients that present with a trisomy 21 (+21).