Crystal structure of human BCL6 BTB domain in complex with compound 12a
收藏Protein Data Bank Japan2024-01-31 更新2026-03-28 收录
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Crystal structure of human BCL6 BTB domain in complex with compound 12a Descriptor: (2~{S})-10-[[5-chloranyl-2-[(3~{S},5~{R})-3-methyl-5-oxidanyl-piperidin-1-yl]pyrimidin-4-yl]amino]-2-cyclopropyl-3,3-bis(fluoranyl)-7-methyl-2,4-dihydro-1~{H}-[1,4]oxazepino[2,3-c]quinolin-6-one, 1,2-ETHANEDIOL, B-cell lymphoma 6 protein, ... Authors: Gunnell, E.A, Le Bihan, Y.-V, van Montfort, R.L.M. Deposit date: 2021-12-17 Release date: 2022-06-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo . J.Med.Chem., 65, 2022
创建时间：
2021-12-17
