False positive report probability.

FPRP values for the nominally significant (p-valueTable 3) and of SNP-smoking interaction effects (Table 4). FPRP is computed according to the formula ��(1?��)/[��(1?��)+(1?��)��], where �� and (1?��) are the P-value and Power values reported in the table, and �� represents the Prior Probability ranging from 0.001 to 0.5. FPRP values less than 0.2 are in italic, FPRP values between 0.2 and 0.5 are bold, and FPRP values larger than 0.5 are the rest.(a)Test for main genetic effect among all subjects.(b)Test for main genetic effect among controls and adenocarcinoma cases.(c)Test for main genetic effect among controls and squamous carcinoma cases.(d)Test for gene-smoking interaction among all subjects.(e)Test for gene-smoking interaction among controls and adenocarcinoma cases.(*)OR indicates the measured odds ratio for the main genetic effect for tests (a), (b), and (c), and the measured odds-ratio ratio for the gene-smoking interaction effect for tests (d) and (e).(**)The statistical power to detect the measured OR given a type I error rate of 0.05 was computed by means of the QUANTO software (http://hydra.usc.edu/gxe).