Growth of established C3 tumors in C57BL/6 mice after treatment with titanium salan complexes 1, 2.

Mice received tumor cells s.c. into the flank and were treated either with 30 mg/kg at multiple applications (m.a.) (days 0, 2, 4, 7, 9, 11 with 5 mg/kg, respectively) (*) or with 50 mg/kg at m.a. (day 0: 30 mg/kg and day 9: 20 mg/kg) (#). Data gives the mean ± SEM at days 0 and 31 and the number of completely tumor free animals. Because of the size of tumors in the control group the experiment was terminated at day 31. One representative of two experiments is shown.