Human poly(ADP-ribose) polymerase 2, catalytic fragment in complex with an inhibitor ABT-888
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Human poly(ADP-ribose) polymerase 2, catalytic fragment in complex with an inhibitor ABT-888 Descriptor: (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, GLYCEROL, Poly [ADP-ribose] polymerase 2 Authors: Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) Deposit date: 2009-11-03 Release date: 2009-11-17 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888. Biochemistry, 49, 2010
创建时间:
2009-11-03



