Dataset for publication "Cell-dependent antithrombotic effect of tranexamic acid" (DOI: 10.3389/fimmu.2026.1820813)

The files contain the raw data used for the respective figures and the self-designed Matlab function used for the evaluation reported in Fig 3 of the paper.Data_Fig1: Mass of thrombi in IVC stenosis shown in Fig. 1 and used in the statistical analysis shown in the supplementary Figures S1, S2, and S3.Data_Fig2: Blood levels of VWF:Ag and MCP-1 48 h after IVC stenosis shown in Fig. 2 and used in the statistical analysis shown in the supplementary Figures S4, S5, S6, and S7.Data_Fig3: Endogenous thrombin potential (ETP) of whole blood following induction of IVC thrombosis (raw data and Matlab function). The file “How to use the TGA system.docx” in the References subfolder contains instructions on how to use the TGA function system. The file “data_file_and_sheet_names.xlsx” in the subfolder “Data/XLSX_files” describes the content of the source Excel files containing fluorescence values for each set of experiments evaluated in Fig. 3.Data_Fig4: Fluorescence of the AMC product released by the generated plasmin in the course of plasminogen activation.Data_Fig5: Cumulative blood loss over 30 minutes in standardized tail bleeding assay performed 48 hours after surgery.