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Ternary complex of CDK2 with small molecule ligands TW8672 and Dinaciclib

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Protein Data Bank Japan2023-10-25 更新2026-05-23 收录
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Ternary complex of CDK2 with small molecule ligands TW8672 and Dinaciclib Descriptor: 1,2-ETHANEDIOL, 2-{[2-(1H-indol-3-yl)ethyl]amino}-5-nitrobenzoic acid, 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium, ... Authors: Schonbrunn, E, Sun, L. Deposit date: 2023-01-03 Release date: 2023-05-31 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding. Nat Commun, 14, 2023
创建时间:
2023-01-03
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