Mâncio Lima malaria cohort study 2018–2021: Prevalence surveys

Malaria is increasingly diagnosed in urban centers across the Amazon Basin. In this study, we combined repeated prevalence surveys over a 4-year period of a household-based random sample of 2,774 persons with parasite genotyping to investigate the epidemiology of malaria in Mâncio Lima, the main urban transmission hotspot in Amazonian Brazil. We found that most malarial infections were asymptomatic and undetected by point-of-care microscopy. Our findings indicate that as malaria transmission decreases, the detection threshold of microscopy rises, resulting in more missed infections despite similar parasite densities estimated by molecular methods. We identified genetically highly diverse populations of Plasmodium vivax and P. falciparum in the region; occasional shared lineages between urban and rural residents suggest cross-boundary propagation. The prevalence of low-density and asymptomatic infections poses a significant challenge to routine surveillance and the effectiveness of malar..., , , # Mâncio Lima malaria cohort study 2018–2021: Prevalence surveys

[https://doi.org/10.5061/dryad.69p8cz9cb](https://doi.org/10.5061/dryad.69p8cz9cb)

## Description of the data and file structure

This dataset contains the data of repeated prevalence surveys over a 4-year period of a household-based random sample of 2,774 persons to investigate the epidemiology of malaria in Mâncio Lima, the main urban transmission hotspot in Amazonian Brazil.

### Variables

| Variable | Description | Field Attributes |
| :------------------------------- | :---------------------------------------------------------------- | :----------------------------------------------------------------------------------------------------------------------------------------------- |
| visit ...