Orexin Receptor 2 (OX2R) in Complex with G Protein and Small-Molecule Agonist Compound 1
收藏Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Orexin Receptor 2 (OX2R) in Complex with G Protein and Small-Molecule Agonist Compound 1 Descriptor: 4'-methoxy-N,N-dimethyl-3'-{[3-(2-{[2-(2H-1,2,3-triazol-2-yl)benzene-1-carbonyl]amino}ethyl)phenyl]sulfamoyl}[1,1'-biphenyl]-3-carboxamide, Engineered Guanine nucleotide-binding protein subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Hong, C, Byrne, N.J, Zamlynny, B, Tummala, S, Xiao, L, Shipman, J.M, Partridge, A.T, Minnick, C, Breslin, M.J, Rudd, M.T, Stachel, S.J, Rada, V.L, Kern, J.C, Armacost, K.A, Hollingsworth, S.A, O'Brien, J.A, Hall, D.L, McDonald, T.P, Strickland, C, Brooun, A, Soisson, S.M, Hollenstein, K. Deposit date: 2020-12-15 Release date: 2021-02-10 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation. Nat Commun, 12, 2021
创建时间：
2020-12-15
