BindingDB Entry 50018286: Molecular hybrids: A five-year survey on structures of multiple targeted hybrids of protein kinase inhibitors for cancer therapy.

Small molecule binding data for protein Apoptosis regulator Bcl-2, Bromodomain-containing protein 4, Casein kinase II subunit alpha, Casein kinase II subunit alpha 3, Cyclin-dependent kinase 10, Cyclin-dependent kinase 2, DNA topoisomerase 1, DNA topoisomerase 2-alpha, DNA topoisomerase 2-beta, Epidermal growth factor receptor, Heat shock protein HSP 90-alpha, Histone deacetylase 1, Histone deacetylase 6, MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase-interacting serine/threonine-protein kinase 2, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Platelet-derived growth factor receptor alpha/beta, Receptor-type tyrosine-protein kinase FLT3, Serine/threonine-protein kinase B-raf, Similar to alpha-tubulin isoform 1, Tubulin beta-4B chain, Tyrosine-protein kinase JAK2, Vascular endothelial growth factor receptor 2, and [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Uniprot O00329, O60674, O60885, P00533, P05622, P07900, P10415, P11387, P11388, P15056, P24941, P26618, P35968, P36888, P42336, P42338, P68371, P68400, Q02880, Q13547, Q15118, Q15131, Q862L2, Q8NEV1, Q9BUB5, Q9HBH9, and Q9UBN7