Epigenetic modifiers are promising targets to improve therapies in patients with cancer. Targeting the methyltransferase DOT1L with small molecule inhibitors has shown promising effects on the control

NIAID Data Ecosystem40

Additional file 8: of Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites

表观遗传学

年龄相关疾病

Table S6. Top enrichment results of age-associated differentially hypermethylated CpG positions (aDMPs) for age-related diseases and quantitative traits. (XLSX 12 kb)

Figshare2019-08-19 更新00

Epigenetic and transcriptomic signature of aging in human liver. Epigenetic and transcriptomic signature of aging in human liver

表观遗传学

转录组学

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem60

Hypo-acetylated Genes of Mouse Clone (C1)

表观遗传学

ChIP-qPCR

The change in acetylation is displayed as both percent change (%) and log (base2) values for the C1 animal relative to D1. Each value represents the average of two replicates ChIP-qPCR assays.

NIAID Data Ecosystem30

Two distinct modes of DNMT1 recruitment ensure the stable maintenance DNA methylation

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相关数据集