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Complex Structure of FXR Ligand-binding domain with a tetrahydroazepinoindole compound

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Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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Complex Structure of FXR Ligand-binding domain with a tetrahydroazepinoindole compound Descriptor: 1-methylethyl 8-fluoro-1,1-dimethyl-3-{[4-(3-morpholin-4-ylpropoxy)phenyl]carbonyl}-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate, Farnesoid X receptor Authors: Xu, W, Lundquist, J.T. Deposit date: 2009-12-11 Release date: 2010-03-02 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Improvement of Physiochemical Properties of the Tetrahydroazepinoindole Series of Farnesoid X Receptor (FXR) Agonists: Beneficial Modulation of Lipids in Primates. J.Med.Chem., 53, 2010
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2009-12-11
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