PERSONALIZED DIFFERENTIAL ALGORITHM FOR METABOLIC SURGICAL MANAGEMENT IN PATIENTS WITH TYPE 2 DIABETES MELLITUS ACCORDING TO BODY MASS INDEX CRITERIA

The global escalation of Type 2 Diabetes Mellitus (T2DM), inextricably linked with the obesity epidemic, necessitates profound interventions that transcend traditional pharmacological management. Metabolic and bariatric surgery has emerged as the most efficacious therapeutic modality for achieving sustained glycemic control and mitigating obesity-related cardiometabolic complications. Recent updates to international guidelines advocate for metabolic surgery in patients with a Body Mass Index (BMI) kg/m² combined with inadequately controlled T2DM. Despite this consensus, the optimal selection of specific surgical procedures remains a complex clinical challenge requiring individualized stratification. This comprehensive research report delineates the development of a differential metabolic surgical treatment algorithm based on body mass index and metabolic severity, specifically comparing the efficacy and safety profiles of One Anastomosis Gastric Bypass (OAGB) and Transit Bipartition (TB). Conducted with reference to a clinical cohort framework established at the 1st City Clinical Hospital in Tashkent, the analysis evaluates the anthropometric, glycemic, and nutritional trajectories associated with both interventions.