Management of Morphea with Topical Therapies: An Evidence-Based Review

Morphea, also known as localized scleroderma, is a rare inflammatory and sclerosing disease with cutaneous and extracutaneous manifestations. Topical therapies are often used alone or in combination with systemic and/or light therapies, depending on disease subtype, extent, and severity. This systematic review examines the use of topical therapies in morphea, with a focus on skin efficacy.