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Crystal structure of SYNT001, a human FcRn blocking monoclonal antibody

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of SYNT001, a human FcRn blocking monoclonal antibody Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ... Authors: Blumberg, R.S, Cheung, J, Mahmood, A, Gandhi, A.K. Deposit date: 2018-12-21 Release date: 2019-12-25 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.381 Å) Cite: Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses. Sci Adv, 5, 2019
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2018-12-21
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