Atopic dermatitis (AD) is an inflammatory, heterogeneous, chronic skin disorder characterized by recurrent eczematous lesions and intense pruritus, and the pathophysiology mechanism of AD is known for
The Salt-Inducible Kinases (SIK) 1-3 are key regulators of pro- versus anti-inflammatory cytokine responses during innate immune activation. The lack of highly SIK-family or SIK isoform-selective inhi
Purpose: T cells undergo intense proliferation in the setting of lymphopenia and chemotherapy pre-conditioning is therefore an essential component of CAR-T therapy. Lymphopenia-induced proliferation (
Ticks are ectoparasites that have co-evolved with their hosts for millions of years. Unlike other blood-feeders, hard ticks take several days to complete a blood-meal, which makes them especially susc
