Association of NP into rafts

There is evidence that NP alone is intrinsically targeted to the apical plasma membrane and associates with lipid rafts in a cholesterol-dependent manner, which suggests that RNPs could reach the assembly site independently of the other viral components.

研究表明，NP（核衣壳蛋白）本身内在地靶向细胞顶端质膜，并以胆固醇依赖的方式与脂筏相结合，这表明核糖核蛋白（RNPs）可以独立于其他病毒成分，到达组装位点。